The main goal of this project is to evaluate the bioreceptivity of the studied stone substrates with different mineralogical, chemical and physical properties and their susceptibility to staining. Furthermore, appropriate procedures will be developed and optimized for the prevention of biodeterioration, which will lead to the development of high bioresistant and stainfree stone surfaces. Research results will be applied in the field of modern buildings, historical buildings and stone monumets and to a minor extent to the preservation of the natural heritage.